The KrosFlo Automatic Backpressure Valve
Available from Spectrum Laboratories
The KrosFlo Automatic Backpressure Valve controls the transmembrane pressure (TMP) or permeate back pressure during tangential flow filtration processes without touching the fluid stream. This makes it ideal for automated process control of single-use TFF processing.
When attached to the flexible tubing retentate line, the valve automatically opens and closes to maintain a user-defined TMP. When attached to the permeate line the valve opens and closes to maintain a user-defined permeate back pressure.
This automatic, self-regulating pressure control valve features programming that controls the pressure through a feedback loop. It is designed specifically for use with single-use, disposable flowpaths. It can control pressures with processing volumes from 1000L to 1ml.
The automatic backpressure valve reduces the chance of membrane fouling and pressure spikes and decreases tangential flow filtration processing time. It is ideal for ultrafiltration and microfiltration applications.
Two sizes of the valve are available, one for use with 1/4" maximum OD flexible tubing and the second for use with 5/8" maximum OD flexible tubing.